Catharanthus roseus (L.) G.Don; Madagascar periwinkle is a popular ornamental plant found in gardens and homes across the warmer parts of the world. The aerial parts of the plant are used for the extraction of the medicinal alkaloids vincristine and vinblastine. Catharanthus roseus is a plant of the Apocynaceae family. It is used as an ornamental. The medicinal properties of C. roseus are attributed to the bioactivity of the above compounds. C. roseus has reportedly been used for centuries by traditional Chinese medicine, to treat a whole range of ailments from diabetes to depression. Medicinal Uses Of Periwinkle Plant Preparations of ajmalicine are used to treat the psychological and behavioural problems of senility, sensory problems (dizziness, tinnitus), cranial traumas and their neurological complications [ 299 ]. Catharanthus roseus •Catharanthus roseus is a popular ornamental plant. cliff faces, rocky ocean ledges and sand dunes) and other sites with sandy soils, but also grows in bushland and disturbed natural vegetation near urban areas. Catharanthus roseus is EXTREMELY toxic in all parts. Catharanthus roseus is a renowned medicinal plant, belonging to the family Apocynaceae; and is a rich source of alkaloids, which are distributed in all parts of the plant. It has also been used for treatment of Alzheimer's disease , , , . It produces over 120 alkaloids, 70 of which are pharmacologically active. Related Links (opens in a new window) This plant thrives in summer heat, and is drought-tolerant once established. Vinblastine and vincristine are used to treat Hodgkin's lymphoma and leukaemia. 2003 Nov;28(11):1006-9. It was brought into cultivation in the first half of the 18th century in Paris from seeds collected in Madagascar, and was later dispersed from European botanical gardens to the tropics as an ornamental. It is also known as the source of chemical compounds used in the treatment of cancer. It is classified as a semi-shrub and can grow up to about 100 cm tall. As the … vinblastine and vincristine. It has attractive, glossy leaves and rose-pink, phlox-like flowers, which bloom from June to frost. C. roseus whole plant as well as individual parts contain diverse types of phytochemicals like alkaloids, phenols, saponins, tannins, terpenoids, steroids, flavonoids etc. In traditional medicine, Catharanthus roseus has been used to treat a variety of ailments in Madagascar as well as in other parts of the world where the plant has naturalized. Cooperative Extension, which staffs local offices in all 100 counties and with the Eastern Band of Cherokee Indians. Catharanthus roseus is a perennial small herb or sub-shrub, up to 90 cm in height. Stem is erect, lax branching with flexible long branches, purple or light green. After the periwinkle was introduced to the southern United States, it has now become an ornamental plant grown in flowerbeds, serving as a great boarder plant. are mainly present in aerial parts whereas ajmalicine, Madagascar periwinkle, rosy periwinkle, bright-eyes, Cape periwinkle, old-maid, periwinkle, pink periwinkle, rose periwinkle, vinca. is a species of the genus Catharanthus in the family Apocynaceae that is used in many herbal medicines preparation. Catharanthus roseus, does an excellent job tolerating the hot temperatures of the summer, and is also able to bear the extremes of drought and heavy rainfall. ... Decoction of all parts is used in the treatment of malaria, skin diseases, Hodgkin's disease, diarrhea, hypertension, and diabetes. (1987) p 140-41 Parts Shown: Flower, Leaf Photo Plants of the World: an Illustrated Encycopedia of Vascular Plants. Parts used: Root/ Leaves: Catharanthus roseus. Cultivars offer additional color choices, including red, purple, and white. A number of alkaloids isolated from this plant are already in clinical use, e.g. Extracts of Catharanthus roseus have been used to effectively treat cancers. The Soxhlet extraction was used to prepare the C. roseus hairy root extract for isolation of vindoline, ajmalicine, serpentine and catharanthine [ 41 ]. It is normally used in cancer chemotherapy. Antimicrobial Activity of Catharanthus roseus – A Detailed Study / Prajakta J. Patil and Jai S. Ghosh / British Journal of Pharmacology and Toxicology 1(1): 40-44, 2010 (17) Advances in the study of vincristine: an anticancer ingredient from Catharanthus roseus / Lu Y, Hou SX, Chen T. / Zhongguo Zhong Yao Za Zhi. Catharanthus roseus is a tropical plant used in traditional herbal medicine in regions of the world where it historically grows. Noteworthy Characteristics. It has attracted increasing attention due to it being shown to possess a range of phytochemicals with various biological activities such as antioxidant, antibacterial, antifungal, antidiabetic and anticancer properties. It has shiny dark green leaves arranged in opposite pairs. C. roseus is used in plant pathology as an experimental host for phytoplasmas. 1837. Catharanthus roseus Linn (Apocynaceae), is a traditional medicinal plant used to control diabetes, in various regions of the world. Folk Remedies and Traditional Uses of Catharanthus roseus are summarized below:  … The plant has been used in traditional medicine since ages in various parts of the world. Catharanthus roseus L (C. roseus) has been used to treat a wide assortment of diseases including diabetes. Catharanthus roseus is an ornamental and medicinal plant, used to treat cancer. Related Objects : Illustration: Illustration . The plant has a long history of use in Ayurvedic medicine, traditional Chinese medicine and other healing systems. Catharanthus roseus Dried leaves Ayurvedic name Nityakalyani (S) Unani name Sada Bahar Hindi name Bara Massi/ Sada Bahar English name Periwinkle Trade name Sada Bahar Parts used Root/ Leaves Morphological Characteristics Catharanthus roseus is a perennial small herb or … Vinblastine and vincristine, used in the Recently, compounds have been discovered in this special plant that have cancer fighting properties. In this study we evaluated the possible antidiabetic and hypolipidemic effect of C. roseus (Catharanthus roseus) leaf powder in diabetic rats. Catharanthus roseus is a tropical plant used in traditional herbal medicine in regions of the world where it historically grows. 4: 95. Catharanthus roseus NC State University and N.C. A&T State University work in tandem, along with federal, state and local governments, to form a strategic partnership called N.C. The objective of our study was to evaluate the antimicrobial and wound healing activity of the flower extract of Catharanthus in rats. Although this method is simple, well established and inexpensive, it is also time consuming and requires large quantities of solvent. (2017) p 526 Parts Shown: Flower, Leaf Photo •This subtropical flowering plant can be grown year round in warm regions. Catharanthus roseus, commonly called periwinkle, Madagascar periwinkle or annual vinca, is an erect to spreading tender perennial in the dogbane family typically mounding 6-18” (less frequently to 24”) tall and as wide.It produces attractive bushy foliage that is covered by an often profuse bloom of phlox-like flowers from summer to frost. the medicinal plant Catharanthus roseus (L.) G. Don, the terpene in-dole alkaloid (TIA) family of natural products includes many valu-able medicinal compounds such as the clinically used antineoplastic agents vinblastine and vincristine, as well as the antihypertensive agent ajmalicine (Figure 1). It has been used as anti-diabetic (flowers and leaves), hypolipidemic and antioxidant. More used as pharmaceuticals, agrochemicals, flavor and fragrance, ingredients, food additives and pesticides. Madagascar periwinkle, the common name of this medicinal and ornamental plant, indicates where the species originated. The alkaloids are prescribed in anticancer therapy, usually as part of complex chemotherapy protocols. This is because it is easy to infect with a large majority of phytoplasmas, and also often has very distinctive symptoms such as phyllody and significantly reduced leaf size. The alkaloids like actineo plastidemeric, Vinblastin, Vincrestine, Vindesine, Vindeline Tabersonine etc. Periwinkle alkaloids have been used to treat certain cancers; however, use of the plant for this purpose is not recommended without consulting a health care provider.Periwinkle has been studied for potential antimicrobial and antiprotozoal applications, as well as for use in diabetes and wound healing; however, there is not enough reliable information to recommend the plant for these uses. This plant has Madagascar Periwinkle is a tender perennial grown as an annual in New Jersey. C. roseus is widely cultivated as an ornamental, but it is also grown for medicinal purposes. Medicinal/Cultural/Economic usage: Catharanthus roseus has been used medicinally in the Lucayan Archipelago to treat circulatory issues. These alkaloids are used to treat cancer (Ajaib et al., 2010) [2]. C. roseus produces vinblastine, utilized in treating Hodgkin’s disease; testicular tumors, breast carcinoma, choriocarcinoma, Kaposi sarcoma and Letterer-Siwe disorder. All parts of the C. roseus are used for different medical purposes. The chemotherapy agent known as vincristine is extracted from Vinca rosea (Catharanthus roseus) is used to treat diseases such as diabetes, leukemias, high blood pressure, lymphomas, stroke, and childhood cancers as well as several other types of cancer and some non-cancerous conditions. Genus : Catharanthus Species : C. roseus (Vinca rosea) Medicinal importance of Catharanthus roseus: Catharanthus roseus is an important medicinal which synthesizes two terpene indole alkaloids viz. The aim of this study was to extract and identify the major constituents, namely, the indole alkaloids, from two Apocynaceae medicinal plant family species, Catharanthus roseus and Vinca minor when using different solvents (the alcohol mixtures, the imidazolium-based ionic liquids (IL) and the novel choline- and menthol-based deep eutectic solvents (DESs)) in ultrasound-assisted processes. Catharanthus roseus has been introduced into new habitats worldwide mostly to be used as an ornamental and a medicinal plant. The leaves and aerial parts of the plant have a wide range of traditional uses. • It is widely used in temperate zones as an annual bedding plant and continues blooming throughout the season. It grows best in well-drained soil. Catharanthus roseus(Madagascar periwinkle). ajmalacine – an anti- Catharanthus roseus (Linnaeus) G. Don, Gen. Hist. Catharanthus roseus Linn. Catharanthus roseus (C. roseus) is an important medicinal plant distributed in many countries. 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